Past Paper for NIPER 2007

Q1 sterioisomer which are not mirror image of each other called?

Ans-diesterioisomer

Q2 biphenyl compound are optically active due to

Ans-atropiisomer

Q3 reaction a____b

Ans-hgso4/zn

Q4 which base is prefferd for elimination ovar substitution

Ans-etoQ5

cyclic chain analogue of sugar is called?

Ans-epimer

Q6 fig a fig b are

Ans-epimer

Q7 compared to p-nitrobenzoic acid, p-methoxybenzoic acid is

Ans-less acid

Q8 hybridisation state of carbanion is

Ans-sp3

Q9 nucleophilic substitution most favourd in

Ans-2, 4, 6, chlorobenzene

Q10 one strioproduct is predominating in which reaction? Ans sterioselective

Q11 1, 1-dimethylcyclohexane is optically due to

Ans-absence of restrication rotation

Q12 reagent use for epoxidation is

ans-cyclopropoxiode

Q13 tropic acid is optically inactive

Ans-absence of chiral centre

Q14 bond length of hydrogen nucei is

Ans-1.2a

Q15 reagent used in benzoin condensation is

Ans-kcn

Q16 which buffer system provide ph 1.6

Ans cetric acid

Q17 pka of drug is 6.7 and ph of medium 7.4 deug is

Ans-positive charge

Q18 ionic product/autoprotolysis, by increase in temptrture

ans-increase

Q19 according to arrhenious theary pseudo base is

Ans-which bring about to donate 0hQ20

monoacidic base is

Ans-base which accept h +

Q21 3d arrangement on 2d paper drawn by

An s-newman pojection

Q22 addition of alkaline and cold kmno4

Ans-1, 2-diol

Q23 hybridisation state of methyl free radical is

Ans-sp3

Q24one q. On sequence rule

Q25geometrical isomer is related to

ans-constitutional isomer

Q26 charged amino acid is

Ans-arginine histine

Q27 geletin have isoelctronic points is

Ans-6.3

Q28 inulin on hydrrolysis to give

Ans-galactosidase

Q29 in protien translation, which amino acid uses

Ans-d. L both

Q30 3d arrangement of protien is

Ans-quaternary struture

Q31 dna folding is

Ans-catalytic phenonmenon

Q32 red colour of blood is due to

Ans-heme and methyl

Q33 degenracy of genetic code is

Ans-code do not overlap

Q34 restrication endonuclease cut

Ans-dna and rna both

Q35 denaturation of protien is by

Ans-heat. Ph, alkali

Q36 brij is

Ans-poly alkoxy sorbitn fatty acid ester

Q37 histocompatibility is associated to

Ans-antigen

Q38letter word for tryptophan is

Ans-t

Q39 for sterlisation becteria following are used

Ans-filtration

Q40 trasfer of genetic material to e. Coli is called

Ans-transduction

Q41 pyruvic acid is enter to mitochondria due to

ans pyruvate dehydrogenase is mitochondrial enzyme

Q42 oxidation of fats by

Ans-b-oxidation

Q43 which will give max amount of energy

Ans-1, gm of fats

Q44 activation energy of reaction is

Ans constant

Q45 which thing is determine in aids thearpy

Ans-cd4 + count

Q46 ion linked receptor are

Ans-gaba, glutamate, ach

Q47 tetracycline given along with

Ans-cimetidine

Q48 which antihypertensive drue is given to patient who is on insulin thearpy

Ans-atenolol

Q49 which drug avalable as transdermal form

Ans-clonidine

Q50 which is extensively metabolised

Ans-lidocaine, propranol

Q51 first pass metabolism occur by

ans-oral rout

Q51 true statement about barbiturates is

Ans-narrow thearpeutic index. Enzyme induction

Q52 benzapril is

Ans-ace inhibitor

Q53 patient suffering from glucoma epilepsy, oedema which drug is prefferd

Ans-acetozolamide

Q54 drug used in mysthenia gravis is

Ans-edrophonium

Q55 muscarinic agonist is

Ans-bethanocol

Q56 muscarinic antagonist is

Ans-atropine

Q57pre systemic metabolism cause

Ans-decearse half of drug

Q58 drug absorption effected by

Ans-food, ph of stomach, dease state

Q59 which factor not affect the drug absorption

Ans-patient colour

Q60 true about renal excretion of drug is

Ans-all drug excreted by glomeralus

Q61 which agent used in removing h. Pylori

Ans-clarithromycin

Q62 sar is

Ans-study about drug struture for chemical steability

Q63 false about metoclopramide is

Ans-decrease prolactine secretion

Q64 morphine heated with con. Hcl give

Ans-aporphine

Q65 a &b chain of insuline is linked by

Ans-sulphide linkage

Q66 sulpher linkage is formed by

ans-by two cystein molecule

Q67 phenyl glycine chain is seen in

Ans-ampicilline

Q68 hall mark of diabetic mellitus is

Ans-hyperglycemia

Q69 which drug used in ceribral maleria

Ans-quinine

Q70 which drug is contraindicated with pyrimethamine is

Ans-quinacrine

Q71 e. Histolytica infective state is

Ans-trpozoite

Q72 which of following cause release of 5ht

Ans-stomach seacretion

Q73 stomatitis is called

Ans-inflamation of gastric mucosa

Q74 allergic response is due towhich antibodies

Ans-iga

Q75 which is true abou non epineohripine

Ans-encrease bp cadiac potential

Q76 asprine causes

Ans-decrease mucose production

Q77 moa of antihyperlipidemic is

Ans-inhibit hmg coa reductase

Q78 due to decrease of phosphate level which level is increase

ans-phosphate

Q79 mannitol is not goven orally due to

Ans-orallt toxicity, unpleasent taste, not absorb orally

Q80 mannitol is

Ans-osmotic diuretic

Q81 andrographolide is obtain from

Ans-kalmegh

Q82 kuktoside is another name of

Ans-gentiana lutea

Q83 camphothicin inhibit

Ans-topoisomearse-1

Q84 which enzyme break down glycosidase bond

Ans-amylase

Q85 subarin is present in

Ans-cork cell

Q86 which is naterually emulsifying agent

Ans-acacia

Q87 drug resistence occuer due to

ans-spontanies mutation

Q88 quality test of suppository is

Ans-melting point, breaking test, dissolution

Q89 sequence of deug dissolutin is

Ans-breaking disintegration, deaggreation dissolution

Q90 nohey whitney equation is for

Ans-drug dissolution

Q91 hydrotrophy is related

Ans-drug solublasition

Q92 hensen paddle test used for

Ans-determination of viscosity of semisolid

Q93 partical size use in sedimention is

Ans-1 − 1200micron

Q94 unit of viscocity

Ans-poise

Q95 relative gravitaional force is ratio of

Ans-rgf/gf

Q96 trandem i s

Q97 ratio of methyl and propyl paraben is

ans-2.5

Q98 for coating which is used

Ans-hpmc& cmc

Q99 monometric is used in

Ans-transdermal system

Q100 autoclave work on

Ans-high pressure

Q101 treated soda lime glass used for preantral purpase in condition of

Q102 ethenyl oxide killed by

Ans-alkalytic dna strand

Q103 de flocculated suspansion is

Ans-dilant system

Q104 vanihing cream is

Ans-emulsion base

Q105 in which system dot pattern observed

Ans-o/w

Q106 calcium phosphate is used as

Ans-compressed vehicle

Q107 garlic contain

ans-diallyl propyl

Q108 binomial nomenclature related

Ans-specise & genus

Q109 disintegration time of uncoated is

Ans-15 minute

Q110 type 1 dissolution appratus is

Ans-rotating basket type