Competitive Exams: Major Diseases and Medicines in Biology

Diseases

  • Cement Disease – Cytosillicosis.

  • Hg – Minamata

  • Phosphorous – Phossy Jaws

  • Textile work us – Byssinosis

  • PCB’s workers – Yusho disease (Japan – 1968) – Swollen eyelids

  • Espundia – Leishmania braziliensis – Mucus membrane

  • Absence of single Lysosomal hydrolase – Hurler’s disease

  • Mononucleosis – Epstein Barr virus

  • Blans – Farism – Premature RBS die (so no malaria)

  • Ouch- Ouch/ Itai - Itai – Cadmium (Japan) – of bone, liver & Lungs

  • Excess F -> Knock Knee disease or Skeletal fluorosis – Hardened joint

  • Al – Alzheimer’s disease (Al Deposition in brain)

  • Gas bubble disease of fish – thermal pollution

  • Cotton Dust – Pneumoconiosis – lung fibrosis – Byssinosis

  • Aropecia – Efficiency of Vitamin B7 – Diencephalon

  • Pompe disease – by the buildup of a complex sugar known glycogen in the body's cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally.

  • Asbestos - asbestosis, lung cancer, mesothelioma

  • Deficiency of vitamin E in poultry – Encephalomalacia

  • Inositol – ‘Spectacle eye’ Condition in rat – Alopecia

Name of organ & infection

  • Trachoma – eye

  • Cholera – Stomach

  • Rabies – Brain

  • Diabetes – Pancreas

  • Typhoid – Intestine

  • Diphtheria – Throat

Genetic disorder Disease

  • Down’s syndrome – 21 trisomy - mental retardation, short body, swelling of tongue, folds of eye

  • Patan syndrome – 13 trisomy – infants are deaf, survrive less than 6 months.

  • Edward syndrome – 18 trisomy – infant’s smaller, elongated skill, malformed ear, receding chin, dislocated hips.

Medicines

  • 6MP – mercaplopurine – leukemia

  • Angina pectoris – nitroglycerin

  • PAS – p-amino salicylicacid - TB

  • Atoxyl – soda salt of arsanilic acid – sleeping sickness

  • Levopoda – Parkinsonism 3(3, 4 -dihydroxyphenyl) L-alanine

  • PGF22 – Uterine Contractions

  • Aderaline – act on α1 α2 β1 β2 (not β3)

  • Non aderaline– act on α1 α2 β1 β2 (not β3)

  • Anti choline esterase – myasthenia gravis.

  • Choline esterase reactivator – paralidomine – organophosphate

  • Mycoplasama – resistant to penicillin

  • Virus – resistant to tetracycline

  • Zydowoden + AZT given for AIDS.

  • Protein synthesis of bacteria & mitochondria – sensitive to chloramphenicol, streptomycin.

  • Cytoplasmic protein synthesis is sensitive Cycloheximide

  • 2-phenyl ethane-hypnotic

  • Cytosine arabinoside – anticancer

  • Ademine arabinoside – antiviral

  • Bayer – 7602 for chagas disease

  • Benzene & penicillin – Syphilis

  • Benzyl benzoate – scabies

  • Ovarian cancers – Vincristine

  • E. gingivalis – Geramycin

  • Tenia solium – aeranil, antigen, yomesen, ccl4, Nexylroesorcinal

  • Amoebic dysentery – Hagyl, metrogyl, emetin, arsenic.

  • Sleeping sickness – Bayer 205, pentamidine, lomidine, melarwopol

  • Kala azar – antimony, gluconate.