CancerSEEK- Detection of Surgically Resectable Cancers with a Multi-Analyte Blood Rest (Download PDF)

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A new blood test that can now detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. Cancer SEEK is the name of the blood test, which is used to detect the eight type of cancers in the early stage.

Image of cancer seek

Image of Cancer Seek

Image of cancer seek

What is Resectable Cancer?

  • When “resectable, ” means that doctor believes that it is likely remove all visible parts of the tumor through surgery.

Other Facts About CancerSEEK

  • The test was first applied to 1005 patients with non-metastatic, clinically detected cancer of

    1. Ovary

    2. Liver

    3. Stomach

    4. Pancreas

    5. Esophagus

    6. Colorectum

    7. Lung

    8. Breast.

  • The tests were positive in a median of 70 % for the eight cancer types.

  • The sensitivities ranged from 69 % to 98 % for the detection of five cancer types (ovary, liver, stomach, pancreas, and esophagus).

  • Earlier there were no screening tests available for average-risk individuals.

  • The specificity of CancerSEEK was > 99%.

  • CancerSEEK localized the cancer to a small number of anatomic sites in a median of 83 % of the patients

  • These cancer types were selected because

    • They are common in the west

    • Did not have any blood test for detection for earlier detection.

Background

  • In the past, the majority of localized cancers can be cured by surgery alone, without any systemic therapy.

  • The approved tests for cancer detection are not blood based, and include colonoscopy, mammography, and cervical sampling

  • The maximum sensitivity of plasma DNA-based tests (“liquid biopsies”) was limited for localized cancers.

- Published/Last Modified on: February 16, 2018

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