Scientists Develops First Biological Pacemaker Using Human Stem Cells (Download PDF)

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Scientists of Canada have developed the first functional pacemaker cells using human stem cells. It can regulate heart beats with electrical impulses. It paves the way for alternate biological pacemaker therapy. A pacemaker is a device which is placed in the chest or abdomen to help control abnormal heartbeats using low-energy electrical impulses.

First functional biological pacemaker from human stem cells

First Functional Biological Pacemaker from Human Stem Cells

First functional biological pacemaker from human stem cells

Main Highlights

  • Pluripotent stem cells have the potential to differentiate into more than 200 different cell types that make up every tissue and organ in the body.
  • These cells can be coaxed in 21 days to develop into pacemaker cells.
  • Researchers had used developmental-biology approach to establish a specific protocol for generating pacemaker cells.
  • These human pacemaker cells were tested in rat hearts and have shown to function as a biological pacemaker.
  •  Activating the electrical impulses that trigger the contraction of the heart.

Note

  • A pacemaker is a device which is placed in the chest or abdomen to help control abnormal heartbeats using low-energy electrical impulses.
  • In general Sinoatrial node pacemaker cells are the primary pacemaker of the heart that controls the heartbeat throughout life.
Biological Pacemaker Research

Biological Pacemaker Research

Biological Pacemaker Research

About Research

  • Learning how to generate pacemaker cells could help in understanding disorders in pacemaker cells.
  • It also provides a cell source for developing a biological pacemaker.
  • Biological pacemakers offers promising alternative to electronic pacemakers.
  • It overcomes their drawbacks as a lack of hormonal responsiveness and adapt to changes in heart size in pediatric patients.
ARTIFICIAL PACEMAKER

ARTIFICIAL PACEMAKER

ARTIFICIAL PACEMAKER

- Published/Last Modified on: December 27, 2016

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