USMLE: Medical Science MCQs (Practice-Test 112 of 135)

Download PDF of This Page (Size: 158K) ↧

1. Consider the following statements: Grading of malignant neoplasm is based on the

   1. extent and spread to adjacent structures.

   2. degree of differentiation of tumour cells.

   3. number of mitoses within the tumour.

   Of these statements

   1. l, 2 and 3 are correct

   2. 1 and 2 are correct

   3. 2 and 3 are correct

   4. 1 and 3 are correct

2. Which of the following mechanisms are involved in the transformation of protooncogenes into oneogenes?

   1. Activation by point mutations.

   2. Activation by translocations.

   3. Activation by gene amplifications.

   Select the correct answer using the codes given below:

   Codes:

   1. 1, 2 and 3

   2. 1and 2

   3. 1 and 3

   4. 2 and 3

3. Actinomycosis is caused by Actinomyces is raeli which morphologically resembles Nocardia sp. Which one of the following will differentiate A. Isaeli from Nocardia sp.

   1. Weak acid-fastness

   2. Strict aerobe

   3. Growth over a wide range of temperature

   4. faculative anaerobe

4. All of the following statements are true in respect of hydatid disease except:

   1. It occurs as a result of infection by Echinococcus granulosus

   2. Eggs in the dog's faeces is the infecting agent

   3. Man is the definite host and he acquires the infection by handling an infected dog

   4. The larval form of Echinococcus granulosus in man causes the disease

5. Match List I (Viruses) with List II (Types of malignancy) and select the correct answer.

   List-I	List-II
   Papilloma virus Epstein Barr virus Hepatitis B virus Herpes simplex virus	Burkitts lymphoma Genital warts Hepatocellular carcinoma Carcinoma cervix

   • A
   • B
   • C
   • D
   1. • 2
      • 1
      • 3
      • 4
   2. • 2
      • 1
      • 4
      • 3
   3. • 1
      • 2
      • 3
      • 4
   4. • 1
      • 2
      • 4
      • 3

6. Match List I (systemic manifestations) with List II (carcinomas) and select the correct answer.

   List-I	List-II
   Flushing of face Polycythemia Trousseaus phenomenon Clubbing of fingers	Realcdilcaminoma Carcinoids Lung cancer Pancreatic carcinoma

   • A
   • B
   • C
   • D
   1. • 2
      • 1
      • 3
      • 4
   2. • 2
      • 1
      • 4
      • 3
   3. • 1
      • 2
      • 3
      • 4
   4. • 1
      • 2
      • 4
      • 3

7. Which of the following are the immune functions of macrophages?

   1. They present antigens to T-cells.

   2. They produce soluble factors including immunoglobulins.

   3. They play a role in immunosurveillance

   Select the correct answer

   1. 1, 2 and 3

   2. 1 and 2

   3. 2 and 3

   4. 1 and 3

8. Consider the following features:

   1. Delayed type of hypersensitive response.

   2. Arthus reaction.

   3. Immune complex disease.

   4. Rejection of allografts.

   Cell mediated immune response would include

   1. 1, 2 and 3

   2. 1 and 4

   3. 2 and 4

   4. 1, 2, 3 and 4

9. Match List-I with List-II and select the correct answer

   List-I (Immunodeficiency disease)	List-II (Nature of deficiency)
   Brutons disease DiGeorges syndrome Hereditary angio neurotic oedema Wiskott-Aldrich syndrome	X-linked aganimaglobulinemia Deficiency of complement inhibitor Combined immunodeficiency T-cell defect

   • A
   • B
   • C
   • D
   1. • 1
      • 4
      • 2
      • 3
   2. • 1
      • 4
      • 3
      • 2
   3. • 4
      • 1
      • 3
      • 2
   4. • 4
      • 1
      • 2
      • 3

10. Match List-I with List-II and select the correct answer

    List-I	List-II
    Anti-uveal antibody Autoimmune thyroiditis Anti-acetylcholine receptor antibody Mitochondria	Hashimotos disease Sympathetic opthal mia Ptimaiy bilary cirrhosis Myasthenia gravis

    • A
    • B
    • C
    • D
    1. • 2
       • 1
       • 3
       • 4
    2. • 1
       • 2
       • 3
       • 4
    3. • 1
       • 2
       • 4
       • 3
    4. • 2
       • 1
       • 4
       • 3

11. Which one of the following types of bodies is seen on microscopic examination of liver in viral hepatitis?

    1. L D Bodies

    2. Asehoffs bodies

    3. Mallorys bodies

    4. Councilman bodies

12. Which one of the following statements is correct?

    1. S. Typhi causes gastroenteritis

    2. S. Paratyphi produces acid and gas on glucose fermentation

    3. Vi antigen is related to virulence

    4. Persistence of Vi-antibody indicates development of carrier state

13. Based on the knowledge of pathogenesis of meningococcal meningitis arrange the following manifestations in order of its appearance in course of the disease

    1. Waterhouse-Friderichsen syndrome.

    2. Rhinitis

    3. Prostration.

    4. Chill and fever

    5. Perechial rash.

    Select the correct answer

    1. 2, 4, 3, 5, 1

    2. 2, 4, 5, 3, 1

    3. 4, 2, 3, 5, 1

    4. 4, 2, 5, 3, 1

14. Toxic manifestations of meningococcal disease are due to

    1. exotoxins

    2. capsular polysaccharides

    3. outer memrane proteins

    4. lipopolysacchandes

15. Match List-I (Malarial Parasite) with List-II (Characteristic) and select the correct answer

    List-I	List-II
    Plasmodium vivax Plasmodium falciparum Plasmodium malarise Plasmodium ovate	Accole forms seen Band-like trophozoite RBCs fimbriate with James dots. RBCs enlarged with Schuffners dots

    • A
    • B
    • C
    • D
    1. • 1
       • 4
       • 3
       • 2
    2. • 1
       • 4
       • 2
       • 3
    3. • 4
       • 1
       • 2
       • 3
    4. • 4
       • 1
       • 3
       • 2