USMLE: Medical Science MCQs (Practice-Test 66 of 135)

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  1. At a heart rate of 80/minute, coronary artery blood flow is greatest

    1. Shortly after the second heart sound is heard

    2. Shortly after the A-V valves close

    3. During the peak of left ventricular ejection

    4. Immediately after the aortic value opens

  2. Which ionic currents (I) are involve in vagus-induced alteration of pacemaker potential?

    1. INa and ICl

    2. INa and IK

    3. ICa and IK

    4. ICa and INa

  3. Consider the following events leading to puberty changes in males

    1. Testestorone secretion

    2. Release of Gonadotrophins

    3. Release of GnRH

    4. Maturation of hypothalamus

    What is the proper sequence of these events?

    1. 3, 4, 2, 1

    2. 4, 3, 1, 2

    3. 4, 3, 2, 1

    4. 3, 4, 1, 2

  4. The type of inhibition seen in cerebellum is

    1. Pre-synaptic inhibition

    2. Post-synaptic inhibition

    3. Renshaw-cell inhibition

    4. Fee forward inhibition

  5. Sensation evoked by impulses generated in a receptor depends upon

    1. type of the stimulus

    2. shape of the action potential

    3. ionic component of action potential

    4. part of the brain activated

  6. Impaired microbial killing in Chediak-Higashi disease is due to

    1. Myelo peroxidase deficiency

    2. NADH oxidase deficiency

    3. No phagolysosom formation

    4. G6PD deficiency

  7. The cell damage in acute inflammation is mostly due to

    1. prostaglandins

    2. leukotrienes

    3. cytokines

    4. nitroc oxide

  8. Which one of the following tumors is not associated with Human Papilloma Virus?

    1. Burkitt's lymphoma

    2. Cancer of cervix

    3. Epidermodysplasia verruciformis

    4. Papillomas on skin

  9. Which among the following is the most potent carcinogen in chemical oncogenesis?

    1. Azo dyes

    2. Nitrosamines

    3. Polycyclic aromatic hydrocarbons

    4. Direct acting alkylating agents

  10. consider the following tumors:

    1. Colonic carcinoma

    2. Carcinoma stomach

    3. Hepatocellular carcinoma

    4. Carcinoma pancreas

    Which of these produce carcinoid syndrome as a systemic manifestation?

    1. 1, 2 and 4

    2. 2 and 4

    3. 2 and 3

    4. 1, 3 and 4

  11. Disseminated Intravascular Coagulation is common in which one of the following Leukemias?

    1. Acute myelocytic leukemia

    2. Acute promyelocytic leukemia

    3. Chronic lymphatic leukemia

    4. Chronic myeloid leukemia

  12. Which of the following factors is involved in the pathogenesis of stable angina pectoris?

    1. Sudden spasm of coronary artery

    2. Platelet thrombi over the atherosclerotic plaque

    3. Rupture of atherosclerotic plaque

    4. Chronic stenosing coronary atherosclerosis

  13. Pyuria with sterile urine culture is typically seen in

    1. Renal tuberculosis

    2. Hydronephrosis

    3. Chronic glomerulonephritis

    4. Chronic pyelonephritis

  14. Which of the following cells react immunologically without prior sensitization?

    1. Cytotoxic T. Lymphocytes

    2. Natural Killer cells

    3. Langerhan's cells

    4. Macrophages

  15. Bactericidal function of eosinophils is due to

    1. Histamine

    2. Lactoferrin

    3. Major basic Protein

    4. Transferrin

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