USMLE: Medical Science MCQs (Practice-Test 74 of 135)

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1. Consider the following characteristic features with reference to stratum basale of epidermis:

   1. Is consists of a single layer of columnar cells

   2. Tonofibrils are contained in the cytoplasm of its columnar cells

   3. New cells are produced in this layer to replace the worn out surface cells

   4. The cells are implicated in the formation of keratin

   Which of the statements given above are correct?

   1. 1, 2 and 3

   2. 1 and 3

   3. 2 and 4

   4. 1, 2, 3 and 4

2. The conjugated bilirubin in plasma is predominantly elevated when there is

   1. Excess production of bilirubin due to hemolysis

   2. Decreased uptake of bilirubin into hepatic cells

   3. Disturbed intracellular protein binding of bilirubin in hepatocytes

   4. Intrahepatic or extrahepatic bile duct obstruction

3. Puromycin which inhibits protein synthesis is a structural analog of

   1. tyrosinyl-tRNA

   2. aminoacyl-tRNA

   3. tyrosinyl-mRNA

   4. aminoacyl-mRNA

4. Which group of the following vitamins play key roles in the citric acid cycle?

   1. Riboflavin, folic acid and pyridoxine

   2. Thiamin, Vitamin B12 and Vitamin B6

   3. Riboflavin, Niacin, Thiamin and Pantothenic acid

   4. Biotin, Riboflavin, Thiamin and Niacin

5. Purine deficiency state in humans is primarily due to deficiency of

   1. Folic acid

   2. Vitamin B12

   3. Vitamin B6

   4. Vitamin A

6. The urine would become clear in patient excreting milky urine by replacing dietary fat with

   1. Monoacyl glycerols

   2. Long chain-length fatty acids

   3. Poly-unsaturated fats

   4. Fatty acids having less than 12 carbons

7. Hydrophobic centre of micelles in intestinal lumen contains

   1. Fatty acids, monoglycerides, cholesterol

   2. Bile salts, bilirubin, biliverdin

   3. Bile salts, Creatinine, lecithin

   4. Amino acids, glucose, urea

8. The infective stage of Ascaris to human beings is

   1. Freshly passed eggs

   2. Rhabditiform larva

   3. Filariform larva

   4. Embryonated eggs

9. Consider the following statements with reference to rheumatoid arthritis:

   1. Females are affected three times more commonly than males.

   2. Presence of HLA-DR 3 allele is associated with the development of side effect of gold therapy.

   3. characteristically there is involvement of distal interphalangeal joints.

   4. Atlanto-axial subluxation may occur due to involvement of upper cervical spine.

   Which of the statements given above are correct?

   1. 1, 2 and 3

   2. 1, 3 and 4

   3. 1, 2 and 4

   4. 1, 3 and 4

10. Consider the following features with reference to amoebic liver abscess:

    1. Right lobe is most commonly involved

    2. Pus contains cysts of Entamoeba histolytica

    3. Metronidazole is the drug of choice

    4. Aspiration of liver abscess should always be done

    Which of the statements given above are correct?

    1. 1, 2 and 3

    2. 1 and 2

    3. 2 and 3

    4. 1 and 3

11. Consider the following statements with reference to status epilepticus

    1. Cerebrospinal fluid cells and protein may increase

    2. Fluctuating level of consciousness, automatic behaviour are observed in complex partial variety

    3. The ictal events are rapidly recurring with no loss of consciousness

    4. Phenytoin in dosage of 20 mg/kg intravenously is the preferred drug

    Which of the statements given above are correct?

    1. 2 and 3

    2. 3 and 4

    3. 1, 3 and 4

    4. 1, 2 and 4

12. Consider the following:

    1. Autosomal dominate inheritance

    2. Early onset of hyperglycemia

    3. Impaired insulin secretion

    4. Autosomal recessive inheritance

    Which of the above are used to diagnose MODY (Maturity Onset Diabetes in the Young)?

    1. 1 and 2

    2. 1, 2 and 3

    3. 3 and 3

    4. 2 and 4

13. Match List I (clinical condition) with List II (Urinary finding) and select the correct answer using the codes:

    List-I	List-II
    Pre-renal azotaemia Ischaemic acute tubular necrosis Ethylene glycol ingestion Atheroemblism	Oxalate crystals Eosinophiluria Muddy brown grannular casts Hyaline casts

    • A
    • C
    • B
    • D
    1. • 2
       • 1
       • 3
       • 4
    2. • 2
       • 3
       • 1
       • 4
    3. • 4
       • 3
       • 1
       • 2
    4. • 4
       • 1
       • 3
       • 2

14. Which one of the following parameters is not used for assessing the Glasgow Coma Scale?

    1. Motor response

    2. Verbal response

    3. Eye opening

    4. Pupillary reflex

15. Match List I (Causative Factor) with List II (ECG Abnormalities) and select the correct answer using the codes:

    List-I	List-II
    Digitalis effect Hypercalcemia Hyperkalemia Hypothermia	Shortened Q. T. Interval sine wave Osborn wave Square root sign

    • A
    • B
    • C
    • D
    1. • 3
       • 2
       • 1
       • 4
    2. • 4
       • 2
       • 1
       • 3
    3. • 3
       • 1
       • 2
       • 4
    4. • 4
       • 1
       • 2
       • 3